A technology entrepreneur in Sydney has helped develop an experimental personalized cancer vaccine for his dog using artificial intelligence tools and genomic analysis.
Paul Conyngham turned to AI after his dog Rosie was diagnosed with cancer in 2024. Initial treatments, including chemotherapy and surgery, failed to stop the tumors from progressing.
Conyngham, an electrical and computing engineer and co-founder of Core Intelligence Technologies, began researching alternative options. Using AI tools, he developed a strategy for identifying potential immunotherapy targets.
ChatGPT helped suggest immunotherapy approaches and pointed him toward researchers at the University of New South Wales Ramaciotti Centre for Genomics. Conyngham later worked with scientists at the university to sequence Rosie’s genome and analyze the mutations driving the cancer.
He also used AlphaFold, an AI system developed by Google DeepMind, to analyze mutated proteins and identify potential targets for treatment.
Development of a Personalized mRNA Vaccine
After analyzing the genomic data, Conyngham collaborated with researchers at UNSW’s RNA Institute to design a custom mRNA cancer vaccine tailored to Rosie’s specific tumor mutations.
The vaccine was developed in less than two months by Pall Thordarson, director of the institute and a specialist in nanomedicine and RNA technologies.
According to Thordarson, the case represents one of the first known examples of a personalized mRNA cancer vaccine created specifically for a dog.
“This is still at the frontier of where cancer immunotherapeutics are,” he said. “What Rosie is teaching us is that personalized medicine can be very effective, and done in a time-sensitive manner, with mRNA technology.”
Rosie received her first injection of the vaccine in December and a booster dose in February. Researchers reported that many of the tumors have since shrunk significantly, although some have not responded to the treatment.
Proud with @UNSWRNA to have been involved & making the mRNA-LNP for Rosie. There are nuances here that the thread below misses but nevertheless, the intersection of RNA technology, genomic & AI poses an opportunity to change the way do medicine and make access more equitable 1/8 https://t.co/lRsBtSNgld
— Palli Thordarson (@PalliThordarson) March 15, 2026
Implications for AI in Medicine
While Rosie’s condition has not been fully cured, her health has improved considerably. According to Conyngham, the dog regained energy within weeks of receiving the treatment.
Researchers caution that the experimental therapy is still at an early stage and may not represent a universal solution for cancer treatment. However, the case demonstrates how AI tools can help accelerate the design of personalized therapies by analyzing genomic data and identifying potential biological targets.
The project also highlights the growing role of AI in biomedical research. Technologies such as protein-structure prediction and large language models are increasingly being used by scientists to analyze complex datasets and propose potential treatment strategies.
Some technology leaders say stories like Rosie’s illustrate how AI could transform the pace of medical discovery. As AI-assisted research tools become more widely available, researchers expect personalized medicine approaches to become faster and more accessible in both veterinary and human healthcare.